Editorial Type:
Article Category: Research Article
 | 
Online Publication Date: Mar 07, 2025

Comparative Mortality in Adrenal Insufficiency Patients

DO
DOI: 10.17849/insm-52-2-1-6.2
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Objective.—

This article presents an analysis of mortality data in individuals with a diagnosis of adrenal insufficiency compared to a matched population from a United Kingdom database.

Background.—

Adrenal insufficiency is an easily treated disease, but if undiagnosed and/or glucocorticoid stress dosing is not appropriately implemented at times of illness, then death may occur.

Methods.—

Tabular data on patients with primary and secondary adrenal insufficiency relative to matched controls was generated using the pixel method on the all-cause mortality graph published in the Ngaosuwan et al study.

Results.—

Calculated annual mortality rates, excess death rates, and interval mortality rates were higher for both primary and secondary adrenal insufficiency compared to matched controls. And the increased mortality risk appeared to be greater in those with primary adrenal insufficiency compared to those with secondary adrenal insufficiency.

Conclusion.—

Those with primary and secondary adrenal insufficiency have increased mortality compared to their matched cohort, especially in the early years after their diagnosis.

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Copyright: Copyright © 2025 Journal of Insurance Medicine

Contributor Notes

Address for Correspondence: Grace E. Ching Sun, DO; gecsun@gmail.com
Correspondent: Grace E Ching Sun, DO Vice President, Medical Director RiverSource Life Insurance Company 9513 Ameriprise Financial Center Routing: S-11-09513, MS#1 Minneapolis, MN 55474
Received: Jan 02, 2025
Accepted: Feb 11, 2025